diff --git a/ns3 b/ns3
index a83212791..925f2e6c1 100755
--- a/ns3
+++ b/ns3
@@ -595,6 +595,11 @@ def configure_cmake(cmake, args, current_cmake_cache_folder, current_cmake_gener
     for (cmake_flag, option_name) in options:
         arg = on_off_condition(args, cmake_flag, option_name)
         if arg:
+            is_on = "=ON" in arg
+            reverse = arg.replace("=ON" if is_on else "=OFF",
+                                  "=OFF" if is_on else "=ON")
+            if reverse in cmake_args:
+                cmake_args.remove(reverse)
             cmake_args.append(arg)
 
     if args.lcov_zerocounters is not None:
diff --git a/utils/tests/test-ns3.py b/utils/tests/test-ns3.py
index ca9db15d6..6e9377add 100755
--- a/utils/tests/test-ns3.py
+++ b/utils/tests/test-ns3.py
@@ -596,6 +596,30 @@ class NS3ConfigureBuildProfileTestCase(unittest.TestCase):
         self.assertEqual(return_code, 2)
         self.assertIn("invalid choice: 'OPTIMIZED'", stderr)
 
+    def test_06_OverwriteDefaultSettings(self):
+        """!
+        Replace settings set by default (e.g. ASSERT/LOGs enabled in debug builds and disabled in default ones)
+        @return None
+        """
+        return_code, _, _ = run_ns3("clean")
+        self.assertEqual(return_code, 0)
+
+        return_code, stdout, stderr = run_ns3("configure -G \"{generator}\" --dry-run -d debug")
+        self.assertEqual(return_code, 0)
+        self.assertIn("-DCMAKE_BUILD_TYPE=debug -DNS3_ASSERT=ON -DNS3_LOG=ON -DNS3_WARNINGS_AS_ERRORS=ON -DNS3_NATIVE_OPTIMIZATIONS=OFF", stdout)
+
+        return_code, stdout, stderr = run_ns3("configure -G \"{generator}\" --dry-run -d debug --disable-asserts --disable-logs --disable-werror")
+        self.assertEqual(return_code, 0)
+        self.assertIn("-DCMAKE_BUILD_TYPE=debug -DNS3_NATIVE_OPTIMIZATIONS=OFF -DNS3_ASSERT=OFF -DNS3_LOG=OFF -DNS3_WARNINGS_AS_ERRORS=OFF", stdout)
+
+        return_code, stdout, stderr = run_ns3("configure -G \"{generator}\" --dry-run")
+        self.assertEqual(return_code, 0)
+        self.assertIn("-DCMAKE_BUILD_TYPE=default -DNS3_ASSERT=ON -DNS3_LOG=ON -DNS3_WARNINGS_AS_ERRORS=OFF -DNS3_NATIVE_OPTIMIZATIONS=OFF", stdout)
+
+        return_code, stdout, stderr = run_ns3("configure -G \"{generator}\" --dry-run --enable-asserts --enable-logs --enable-werror")
+        self.assertEqual(return_code, 0)
+        self.assertIn("-DCMAKE_BUILD_TYPE=default -DNS3_ASSERT=ON -DNS3_LOG=ON -DNS3_NATIVE_OPTIMIZATIONS=OFF -DNS3_ASSERT=ON -DNS3_LOG=ON -DNS3_WARNINGS_AS_ERRORS=ON", stdout)
+
 
 class NS3BaseTestCase(unittest.TestCase):
     """!